| abstract |
PURPOSE: To provide a remedy for hepatic disease containing unsubstituted or alkyl-substituted 1,3-benzodioxol as an essential component, exhibiting by far strong remedying activity to hepatic disease compared with known compound having methylenedioxy group, and having high safety. n CONSTITUTION: The objective remedy for hepatic disease contains the compound of formula I (R 1 and R 2 are H or 1W5C saturated alkyl) as an essential component. The compound of formula I has strong activity to cure hepatic disease compared with the compound having methylenedioxy group in the molecule and known as a remedy for hepatic disease, e.g. the compound of formula II, formula III, etc. Furthermore, it has no mutagenecity in contrast with safrole. Dose; preferably 1W10mg/kg daily for oral administration and 0.5W5mg/kg daily for parenteral administration. n COPYRIGHT: (C)1987,JPO&Japio |