http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62292779-A

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-36
filingDate 1986-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46675a6e36606026dc3d89ac8898923d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c6271aa7a69f61a193ad6881902d28
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publicationDate 1987-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S62292779-A
titleOfInvention Substrate for measuring aryl esterase activity
abstract NEW MATERIAL:A 1,3-dioxol-2-one derivative shown by formula I [R 1 is H or lower alkyl; R 2 is (substituted)phenyl]. n EXAMPLE: 4-(4-Fluorophenyl)thiomethyl-5-methyl-1,3-dioxol-2-one. n USE: A substrate for measuring aryl esterase activity in blood in diagnosis for liver diseases, especially liver cirrhosis. n PREPARATION: A compound (e.g. 4-chloromethyl-5-methylo-1,3-dioxol-2-one, etc.) shown by formula II (X is halogen) is reacted with a compound (e.g. 4- fluorothiophenol, etc.) shown by the formula R 2 SH in a nonpolar solvent such as dichloromethane, etc., preferably in the presence of a base such as triethylamine, etc., usually at 0W40°C for 10minW4hr. n COPYRIGHT: (C)1987,JPO&Japio
priorityDate 1986-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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