http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62292777-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb4ee28d43b5e8d4a3c5141fa9bcfeb0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
| filingDate | 1986-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa50b96d0686fb4513690f914a6c31c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a0ed056872066151bb9590056738abe |
| publicationDate | 1987-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62292777-A |
| titleOfInvention | Fluorine-containing coumarones |
| abstract | NEW MATERIAL:A fluorine-containing coumarone shown by formula I (R is 1W16C alkyl; R 2 , R 3 and R 4 are H, F, 1W5C alkyl or 1W8C fluoroalkyl; with the proviso that at least one of R 2 , R 3 and R 4 shows F or 1W8C fluoroalkyl). n EXAMPLE: 8-Iodo-2,2,5,7-tetramethyl-6-acetoxycoumarone. n USE: Useful as an agent for lowering cholesterol, a remedy for arteriosclerosis, etc. n PREPARATION: For example, as shown the reaction formula, a compound shown by formula II as a starting substance is simultaneously reacted with iodine and silver trifluoroacetate in a halogen solvent such as chloroform, etc., at room temperature and H at the 5-, 7- or 8-position is converted into iodine atom. Then the reaction product is reacted with a trifluoroalkyl iodide and copper and the reaction product obtained by the second process is hydrolyzed to give a compound shown by formula I. n COPYRIGHT: (C)1987,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0445827-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7514461-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9515957-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8044097-B2 |
| priorityDate | 1986-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.