http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62289559-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
| filingDate | 1986-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3dbab353fb95f932ae1d50caafeba46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8043c3660f369a10a36415466c0a9d84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ea45cd80f9d955df0167686da0f4d62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd5f707728f7eee1f2296d48d12256fb |
| publicationDate | 1987-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62289559-A |
| titleOfInvention | Production of fluorine-containing azetidinone |
| abstract | PURPOSE: To obtain a 3-[(1R)-hydroxyethyl]azetidin-2-one derivative in high efficiency, by reacting the corresponding 3-[(1S)-hydroxyethyl]azetin-2-one derivative with trifluorodiethylaminosulfuric acid. n CONSTITUTION: The objective (3R,4R)-4-[3-(4-nitrobenzyloxycarbonyl)-3-diazo-2- oxopropan--1-yl]-3-[(1R)-fluoroethyl]azetidin-2-one of formula II useful as an intermediate for a fluorine-containing carbepenem antibiotic substance is produced in high efficiency with an economical process, by reacting 1mol of 3-[(1S)- hydroxyethyl]azetidinone with 1W5mol, preferably 1W2mol of trifluorodiethylaminosulfuric acid in an inert organic solvent such as halogenated hydrocarbon, ether, etc., especially in methylene chloride, preferably at -80W0°C. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1986-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.