http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62258355-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47d14ab9b288f4dbc7f01e02b92d223c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-80 |
| filingDate | 1986-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a685cc151658ff967da7d84fe3bfbd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef7620795026c4d6e9c99212bac96f4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4a55fc21c7edb9036016999082bde4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ae96ca9589c26663b8cacc14ec61b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54b7f2f64e11f256c21e6f6a81c65f0b |
| publicationDate | 1987-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62258355-A |
| titleOfInvention | Nitrogen-containing heteroanthracycline derivative and production thereof |
| abstract | NEW MATERIAL:A compound expressed by formula I (R 1 is trialkylsilylethynyl and R 2 is H or R 1 is acyl and R 2 is OH; R 3 is lower alkyl). n EXAMPLE: cis-9-Acetyl-5-methyl-7, 9, 11, 12-tetrahydroxy-8,9,10,11-tetrahydronaph tho[2,3-b]-carbazole-6,13-dione. n USE: A carcinostatic agent. n PREPARATION: A compound expressed by formula II is reacted with a compound expressed by formula III (A is lower alkylene) to give a ketal compound, which is then reacted with a halogenating agent together with a radical-forming reagent and then subjected to hydroxyl substitution reaction to afford a dihydroxycyclohexaneketal compound having OH group introduced into the 11-position. The resultant compound is then reacted with a ketal eliminating agent to provide the aimed compound expressed by formula I (R 1 is acyl and R 2 is OH), etc. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1986-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419579030 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID222 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397310 |
Total number of triples: 21.