http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62258330-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-31 |
| filingDate | 1986-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c78d50133246ed8b24f359ce49c9f0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45b45e663ab3ee9bb0604b862f44baa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08cc131ed8a82d49cd5d79f8e408787e |
| publicationDate | 1987-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62258330-A |
| titleOfInvention | Production of 6,7-disubstituted-2-hydroxy-3-methylenebicyclo(3.3.0)octane |
| abstract | PURPOSE: To efficiently obtain the titled substance useful as a key intermediate for prostaglandins I 1 , by cyclizing a propargylcylcopentane with a reducing agent using an alkali (earth) metal and, as necessary, deprotecting the reduction product. n CONSTITUTION: A compound expressed by formula I (R 11 and R 21 are tri 1W7C hydrocarbonsilyl or a group together with O of the hydroxyl group forming acetal bond; R 3 is H, CH 3 or vinyl; R 4 is alkyl, alkenyl, phenyl, etc.; n is 0 or 1) or an enantiomer thereof is cyclized with a reducing agent using an alkali (earth) metal and, as necessary, deprotected to give a compound expressed by formula II. The compound expressed by formula I is used in a molar amount of preferably 1.2W10.0 times based on 1mol compound expressed by formula I and as an anion radical solution containing naphthalene, etc., in an amount equimolar or more with the alkali (earth) metal and THF, etc., as a solvent. n COPYRIGHT: (C)1987,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9407838-A1 |
| priorityDate | 1986-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.