http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62252792-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 |
| filingDate | 1986-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfaae097c73211dbb6148a67c39c9c6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_459e19835494d34f9eb8b1924a10b247 |
| publicationDate | 1987-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62252792-A |
| titleOfInvention | Production of 3-alkanoyloxymethyl-3-cephem-4-carboxylic acid compound |
| abstract | PURPOSE: To obtain the tiled compound useful as an antibiotic substance or its synthetic intermediate on an industrial scale at a low cost, by reacting a hydroxymethyl-cephem-carboxylic acid with a saturated fatty acid anhydride in an aqueous solvent in the presence of an acid-absorbing base and a specific compound. n CONSTITUTION: The objective compound can be produced by reacting (A) a 3-hydroxy-3-cephem-4-carboxylic acid [preferably the compound of formula (M is H or salt-forming group), e.g. 7-(D-5-carboxy-5-phthalimidovaleramido)-3- hydroxymethyl-3-cephem-4-carboxylic acid ditriethylamine salt, etc.] with (B) a saturated fatty acid anhydride (e.g. acetic anhydride) in an aqueous solvent in the presence of (C) an acid-absorbing base (e.g. triethylamine) and a 4-(t- amino)pyridine [e.g. 4-(dimethylamino)pyridine] preferably at -20W+20°C for 0.5W1.5hr. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1986-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.