http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62249998-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1986-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c6dd615cfa4ab9dac0d540750b17a76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f82b3498207721729525f66791bc2416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d31485e5ba8e3b0dbe0162c4f17165d7 |
| publicationDate | 1987-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62249998-A |
| titleOfInvention | Production of steroid |
| abstract | PURPOSE: To efficiently obtain a steroid as a synthetic intermediate for adrenocortical hormones in high yield in a small number of steps, by reacting a steroid having a specific partial structure with a silicon hydride compound in the presence of a rhodium catalyst, etc. n CONSTITUTION: A steroid having a partial structure expressed by formula I (R 1 is alkyl), preferably 3β-hydroxypregna-5,16-dien-2-one, pregna-4,16-dien-3,20- one or pregna-4,16-diene-3,11,20-trione, is reacted with a silicon hydride compound expressed by the formula HSiR 2 R 3 R 4 (R 2 WR 4 are alkyl), preferably triethylsilane or tripropylsilane, in a molar amount of preferably 1.1W1.3 times based on the steroid in the presence of a rhodium compound, preferably triphenylphosphinerhodium chloride, or nickel compound, e.g. nickel cyclooctadiene complex, in a catalytic amount to afford the aimed compound having the partial structure expressed by formula II. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1986-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.