http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62249927-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7c7159366be37ecf8a4c595cfa235a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 1986-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba2dbe38e552b5b1cce139bb00067bf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec226c04842df0a56d1bf183746dabc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2984a54c41dab64e9c8b5521e1743e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfd0bf8f6b6eb391d8b9bdb5d30f9357 |
| publicationDate | 1987-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62249927-A |
| titleOfInvention | Proteinous substance and antitumor agent |
| abstract | NEW MATERIAL:A proteinous substance having a main component molecular weight of 15,000W20,000 and obtained by physically disintegrating toxoplasma, subjecting the resultant water-soluble component to ultra-high-speed centrifugal separation and separating from the supernatant liquid. n USE: An antitumor agent exhibiting remarkable antitumor activity even against allogenic tumor, isogenic tumor and autologous tumor. A synergistic effect can be achieved by the combined use with an immuno-activating substance ovioactin. It is easily soluble in water in contrast with an IFN-inducing agent disclosed in Japanese Patent Applitation No.59-27832. n PREPARATION: Toxoplasma (e.g. Toxoplasma gondii) is diluted with distilled water and disintegrated by ultrasonic treatment at 4W15°C for 3W5min. The insoluble components in the disintegrated product is optionally removed by centrifugal separation (e.g. at 16,000 G and 4°C for 60min) and the product is converted to isotonic solution with NaCl and subjected to ultra-high-speed centrifugation at ≥100,000 G (e.g. at 4°C for 120min). The objective proteinous substance containing a main component having a molecular weight of 15,000W20,000 can be obtained as the supernatant liquid. n COPYRIGHT: (C)1987,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013543493-A |
| priorityDate | 1986-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.