| abstract |
NEW MATERIAL:4-(5-Ethyl-2-thienyl)-4-oxo-2-butenoic acid expressed by the formula. n USE: With an antiulcer action and powerful gastric mucosal protective action and useful for treating and preventing gastrointestinal inflammatory diseases, e.g., gastritis, gastric ulcer, duodenal ulcer and hemorrhage of the upper digestive tracts. n PREPARATION: 2-Ethylthiophene as a raw material is reacted with maleic anhydride, etc., in the presence of an acid, e.g., Lewis acid, etc., to afford the aimed compound expressed by the formula. n COPYRIGHT: (C)1987,JPO&Japio |