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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-02
filingDate 1986-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b243245671658f752ce114123f7d6d96
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publicationDate 1987-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S62238267-A
titleOfInvention 9-bromomethylacridine
abstract NEW MATERIAL:9-Bromomethylacridine of formula. n USE: Useful for the analysis of carboxylic acids by using as a fluorescent and UV-absorption labeling reagent. Since the reaction product of the compound of formula and carboxylic acid has extremely high molecular extinction coefficient, carboxylic acid can be determined in high sensitivity. A high-intensity emission line of a deuterium lamp can be used as a fluorescent detector to enable high-sensitivity detection. It can be applied not only to fatty acid but also to a carboxyl-containing compound such as prostaglandin, leucotriene, etc. Applicable also for the analysis of carboxylic acid in blood and living tissue, etc. n PREPARATION: Diphenylamine is heated in acetic acid in the presence of a catalyst and the resultant 9-aminoacridine is refluxed in an organic solvent in the presence of a radical reaction initiator and a bromination agent under heating, left to cool and recrystallized to obtain the objective compound of formula. n COPYRIGHT: (C)1987,JPO&Japio
priorityDate 1986-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.