http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62228058-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5dfc0b033ac4c841466d97a5f28ea32b
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056
filingDate 1986-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36110d3dd9c00ad88cb87f5bea5c3775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a231c143931ea740b35cadf67a06bce1
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publicationDate 1987-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S62228058-A
titleOfInvention Novel isoindoline derivative and production thereof
abstract NEW MATERIAL:The compound of formula I (R is H, lower alkyl, alkanoyl, aralkyl, alkylsulfonyl or arylsulfonyl; R 1 is H or OH-protecting group) or its salt. n EXAMPLE: 5,6-Dihydroxyisoindoline. n USE: Useful as an intermediate raw material for a cephalosporin derivative (an antibacterial agent) having 5,6-dialkanoyl-2-methylisoindoliniomethyl group. n PREPARATION: The compound of formula I can be produced by reacting the compound of formula II (R 2 is OH-protecting group; R 3 is lower alkyl, aralkyl or alkyl- or arylsulfonyl) with formaldehyde and hydrogen halide, dehydrohalogenating the obtained compound of formula III (X is halogen; n is 0 or 1) to the compound of formula IV, removing the protecting group, if necessary, and subjecting the product successively to acylation, N-alkylation and N-aralkylation reactions. n COPYRIGHT: (C)1987,JPO&Japio
priorityDate 1985-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 23.