http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62228058-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5dfc0b033ac4c841466d97a5f28ea32b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-44 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 |
filingDate | 1986-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36110d3dd9c00ad88cb87f5bea5c3775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a231c143931ea740b35cadf67a06bce1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ec7800d6ccc9a18ff8fe3a1de2af4b1 |
publicationDate | 1987-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S62228058-A |
titleOfInvention | Novel isoindoline derivative and production thereof |
abstract | NEW MATERIAL:The compound of formula I (R is H, lower alkyl, alkanoyl, aralkyl, alkylsulfonyl or arylsulfonyl; R 1 is H or OH-protecting group) or its salt. n EXAMPLE: 5,6-Dihydroxyisoindoline. n USE: Useful as an intermediate raw material for a cephalosporin derivative (an antibacterial agent) having 5,6-dialkanoyl-2-methylisoindoliniomethyl group. n PREPARATION: The compound of formula I can be produced by reacting the compound of formula II (R 2 is OH-protecting group; R 3 is lower alkyl, aralkyl or alkyl- or arylsulfonyl) with formaldehyde and hydrogen halide, dehydrohalogenating the obtained compound of formula III (X is halogen; n is 0 or 1) to the compound of formula IV, removing the protecting group, if necessary, and subjecting the product successively to acylation, N-alkylation and N-aralkylation reactions. n COPYRIGHT: (C)1987,JPO&Japio |
priorityDate | 1985-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.