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filingDate 1986-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af1b1990a8171711caa8bf793791e247
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publicationDate 1987-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S62215524-A
titleOfInvention Anti-inflammatory agent
abstract PURPOSE: An anti-inflammatory agent, consisting of a specific indoleacetic acid derivative or salt thereof and having better anti-inflammatory action than that of conventional indoleacetic acid derivative based anti-inflammatory and analgesic agents with slight side effect on gastrointestinal tracts. n CONSTITUTION: An anti-inflammatory agent consisting essentially of an indoleacetic acid derivative expressed by the formula (R 1 is F or perfluoroalkyl and plural may be substituted at the phenyl ring) or a salt thereof. Specific examples include 1-(4-fluorobenzoyl)-5-methoxy-2-methyl-1H-indoleacetic acid, etc. The compound expressed by the formula is capable of exhibiting improved anti-inflammatory action on mammals with very low toxicity thereof. For example, the compound exhibits higher inhibitory action than that of indomethacin and the toxicity is about 1/3 of that of the indomethacin on the other hand. Furthermore, the anti-inflammatory action is about twice based on acemetacin and the toxicity is about 1/4 thereof. n COPYRIGHT: (C)1987,JPO&Japio
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type http://data.epo.org/linked-data/def/patent/Publication

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