| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f4c2477bdea308bc9dec3feded37457 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate |
1986-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe00bd8f759c047e1104d3511bd70cfc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_291f26c44c8bf0cacdd62a7a35520a43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c6886e847d12700c80993cdab38798e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6241125e26cfb22378562ee5e7b36ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4c99ac2d1b65a825279604196beb4c5 |
| publicationDate |
1987-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S62190122-A |
| titleOfInvention |
Aqueous solution containing stable scopolamine hydrobromide |
| abstract |
PURPOSE: To provide an aqueous solution containing scopolamine hydrobromide and having improved stability of the solution, by adding taurine under neutral pH condition. n CONSTITUTION: An aqueous solution of scopolamine hydrobromide is compounded with taurine and optionally glycerol or sorbitol at 5W6 pH. The stability of scopolamine hydrobromide is highly dependent upon the pH of its aqueous solution and is high at 3W4 pH. However, the stability, especially hydrolysis stability of scopolamine hydrobromide causes a problem when an aqueous solution of neutral pH (i.e. 5W6 pH) is to be prepared. The hydrolysis of scopolamine hydrobromide can be suppressed by the addition of taurine or taurine and glycerol, etc. The amount of taurine is preferably e.g. 0.02W0.2 M concentration. n COPYRIGHT: (C)1987,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005075735-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112315906-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102366402-A |
| priorityDate |
1986-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |