http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62187467-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 1986-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14a51079338b090eb57667a47fe249d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_136e819047ce8e117891be6c31354445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d22a14a853670198f664d389bce6b22 |
| publicationDate | 1987-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62187467-A |
| titleOfInvention | Novel production of 4-acetylisoquinoline compound |
| abstract | PURPOSE: To economically obtain the titled compound, having cardiotonic action and useful as an anticardiac failure remedy with little side effect in a short process, by condensing 2-acetyl-4-pyridylcyclohexanone with acetamide as starting raw materials. n CONSTITUTION: 2-Acetyl-4-pyridylcyclohexanone is condensed with acetamide in the presence of a base, e.g. ammonia, methylamine, 1,8-diazabicyclo[5.4.0]-7- undecene, etc., in a suitable solvent, preferably water, methanol, ethanol, etc., at a reaction temperature of a low temperature W the boiling point of the solvent used, preferably as low a temperature as possible to affored the aimed compound. If a secondary amine is used as the solvent, the amount of formed by-products is smaller than in other solvents even at a high temperature. If recrystallization is carried out in a solvent, e.g. methanol, etc., a compound, expressed by the formula and formed as a by-product can be readily removed. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1986-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.