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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
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filingDate 1986-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf8762d496b5f8603e774fcc47b3cf07
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publicationDate 1987-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S62174017-A
titleOfInvention 1,4-dihydropyridine derivative
abstract PURPOSE: To provide a remedy for circulatory diseases, by using a specific 1,4-dihydropyridine derivative as an active component. n CONSTITUTION: 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzyl-3-piperidyl) ester 5-methyl ester having a melting point of 197W198°C (as hydrochloride) or its salt is used as an active compound. The compound used as an active component has hypotensive action, coronary vasodilating action, peripheral vasodilating action, etc., and is useful as a circula tory drug such as hypotensor, vasodilator, etc. The objective compound can be produced by converting the compound of formula I to corresponding acid halide with a halogenation reagent and reacting the acid halide with 1-benzyl-3- judroxy-piperidine of formula II preferably at -20W+50°C. n COPYRIGHT: (C)1987,JPO&Japio
priorityDate 1986-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 26.