http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62174017-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9036c33bbe3f4ea428655b76200f7c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
filingDate | 1986-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf8762d496b5f8603e774fcc47b3cf07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff377f61278d6f5252c6ed0a3894d2ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da3a2e497c7e59ca0c9bdb767b288e5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c742cb077c7d5c6c1582ee54b6f76abd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b420039ef60c805fdba878b52c43ad2 |
publicationDate | 1987-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S62174017-A |
titleOfInvention | 1,4-dihydropyridine derivative |
abstract | PURPOSE: To provide a remedy for circulatory diseases, by using a specific 1,4-dihydropyridine derivative as an active component. n CONSTITUTION: 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzyl-3-piperidyl) ester 5-methyl ester having a melting point of 197W198°C (as hydrochloride) or its salt is used as an active compound. The compound used as an active component has hypotensive action, coronary vasodilating action, peripheral vasodilating action, etc., and is useful as a circula tory drug such as hypotensor, vasodilator, etc. The objective compound can be produced by converting the compound of formula I to corresponding acid halide with a halogenation reagent and reacting the acid halide with 1-benzyl-3- judroxy-piperidine of formula II preferably at -20W+50°C. n COPYRIGHT: (C)1987,JPO&Japio |
priorityDate | 1986-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.