http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62164662-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bba0a34651fd8cd73cf83e6a9effe12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 |
filingDate | 1986-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e390d36aae26daa893cc3435ed87100 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ed32e70846983304ae0c6717986cd19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_745e4c96693d5a78845eb1c05a142009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbb3f5c2b92e479e244fe0f152852680 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50af4edf65a4a6698802f51b6f4be683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c86adfdcf700e2b26638c8b51e1e0d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a09469be6050b3bb588c65ba8005d35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a390f34b9f7837789ce9a11925e4f3f4 |
publicationDate | 1987-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S62164662-A |
titleOfInvention | Azacycloalkane derivative |
abstract | NEW MATERIAL:An azacycloalkane derivative expressed by formula I (R is alkyl; m is 2W4; n is 2W15). n EXAMPLE: 1-(6-Pentyloxycyclohexyl)azacyclopentan-2-one. n USE: Capable of being blended with an absorption accelerator useful for the pharmaceutical industry or cosmetics, e.g. quasi-drugs, etc., and agricultural chemicals, insecticides, etc., having improved enhancing action on penetrability and permeability of drugs into biomembranes, e.g. skin, mucosa, etc., and further individual antimicrobial action and high safety with very weak local irritancy to the biomembranes and systemic toxicity, etc. n PREPARATION: For example, a compound expressed by formula IV is reacted in the presence of an alkali catalyst, etc., to form a compound expressed by formula II (M is alkali metal ion), which is then reacted with a compound expressed by formula V (X is halogen, mesyl, etc.) to afford a compound expressed by formula III. The resultant compound expressed by formula III is further reacted with an alcohol expressed by the formula R-OH in the presence of an alkali catalyst to give the aimed compound expressed by formula I. n COPYRIGHT: (C)1987,JPO&Japio |
priorityDate | 1986-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.