Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620ecb9324409347c27e96b6071503ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 |
filingDate |
1986-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd5a501804588bd55d2ffd474a15216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d268b3c20335f63238b967ae8c8680a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4889f0815a381caaf848bafe73a7833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c4d9e75fb72a1066f774a7524471d6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88aa150d6373a87863d44f3df2e26a46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f78ff99d5413d138a9ae34a306488e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_840a432842f0c7a300b3949fec723a55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cff5c671749f21bd4f1b94969305e2db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d9faadfd0a117af9997d56ebeccd464 |
publicationDate |
1987-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-S62142184-A |
titleOfInvention |
Novel 7-amino-3-1-substituted pyridinio thiomethyl-delta3-cephem derivative and production thereof |
abstract |
NEW MATERIAL:A compound shown by formula I (Ra is lower alkyl; Rb is H or Ra; n is 1-3) or its salt. EXAMPLE:7-Amino-3-(1-acetonyl-4-pyridinio)thiomethyl-DELTA<3>-cephem-4 -carboxylate. USE:An intermediate for cephalosporin antibiotics such as a compound shown by formula VI, etc. PREPARATION:A compound shown by formula II (R<1> is halogen or lower acyloxy; R<2> is H or carboxy-protecting group; R<3> is H or amino-protecting group) on its salt is reacted with a 1-substituted-3-mercaptopyridinium shown by formula III (Z(-) is anion) or a 1-substituted -2- or 4-thiopyridone shown by formula IV or formula V in an inert solvent optionally in the presence of a reaction promoter, deprotected when the reaction product has a protecting group, to give a compound shown by formula I. |
priorityDate |
1985-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |