http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62132845-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5dfc0b033ac4c841466d97a5f28ea32b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 1985-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e75b70fa8d4c46033547e20e3d94ab7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ec3f6de83fe8e580ab83c92923a619c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48028027812b4d8144f2fbfa366e4ba6 |
| publicationDate | 1987-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S62132845-A |
| titleOfInvention | N,n-disubstituted phenylserine derivative and agent for central nervous system containing said compound as active component |
| abstract | NEW MATERIAL:The compound of formula I (R 1 is lower alkyl; R 2 is lower alkyl or aralkyl; R 3 is H or lower alkyl). n EXAMPLE: N,N-dimethyl-3-(3,4-dihydroxyphenyl)serine. n USE: A remedy for central nervous diseases. It exhibits suppressive effect against the lowering of body temperature and blepharoptosis caused by recerpine and is useful as a remedy for depression, parkinson's disease, senile dementia, etc. n PREPARATION: The compound of formula I can be produced by reacting the compound of formula II (R a is protective group of aromatic hydroxyl group) with the carbonyl compound of formula III (R b and R c are H, lower alkyl, etc.) in a solvent such as methanol, treating the reaction product with a reducing agent such as sodium cyanoborohydride and deprotecting the resultant N,N- disubstituted-phenylserine derivative of formula IV. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1985-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.