http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62103061-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
filingDate | 1985-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d16ea1ecf2b50368b0ff482feddb1a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 |
publicationDate | 1987-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S62103061-A |
titleOfInvention | Production of 16-substituted prostaglandin e |
abstract | PURPOSE: To obtain the titled compound useful as pharmaceuticals from an easily available raw material in short steps and high yield, by selectively reducing the 7,8-double bond of a 16-substituted-Δ 7 -prostaglandin E compound. n CONSTITUTION: The objective compound of formula II can be produced by selectively reducing the 7,8-double bond of a 16-substituted-Δ 7 -prostaglandin E compound with a hydrogenated organotin compound (e.g. tributyltin hydride) at 0W200°C. The starting prostaglandin E compound is a compound of formula I [R 1 is COOR 2 , CH 2 OR 3 or COCH 2 OR 3 (R 2 is H, 1W10C alkyl, phenyl, etc.; R 3 is H, tri(1W7C hydrocarbon)silyl, etc.); R 4 and R 5 are H, tri(1W7C hydrocarbon)silyl, etc.; R 6 is H, 1W4C alkyl or vinyl; R 7 is (O-containing) 3W6C alkyl, alkenyl, phenyl, etc.; Y is CH 2 X or XCH 2 (X is ethylene, cis- or trans- vinylene, etc.)], its enantiomer or their mixture at arbitrary ratio. n COPYRIGHT: (C)1987,JPO&Japio |
priorityDate | 1985-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.