http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6210036-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ff914937eb6ceaee5ca69cc56cbfa7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00 |
| filingDate | 1985-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf28139f709404f4461311b41f17f3b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbaeab10ef0303719c2d45fd9382c30a |
| publicationDate | 1987-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6210036-A |
| titleOfInvention | Production of alpha-substituted ketone |
| abstract | PURPOSE: To obtain the titled compound useful as a synthetic intermediate for pharmaceuticals and agricultural chemicals, easily in high yield, under mild reaction condition, by reacting a diazonium salt to a silyl enol ether producible easily from a ketone. n CONSTITUTION: The objective α-substituted ketone of formula III such as benzyl phenyl ketone can be produced by (1) reacting (A) a silyl enol ether of formula I (R 1 WR 3 are H or organic group; R 5 WR 7 ) are alkyl, aryl or aralkyl) [e.g. (1-phenylethenyl)oxytrimethylsilane] with (B) a diazonium salt of formula II (R 4 is aryl or heterocyclic group; X is anion forming a diazonium salt) (e.g. benzenediazonium tetrafluoroborate) in a solvent such as pyridine at -50W+50°C, (2) removing diazonium salt from the resultant reaction solution e.g. by washing with water, (3) removing the solvent e.g. by distillation, and (4) separating and purifying the objective α-substituted ketone of formula III having aryl or heterocyclic group at the α-site (e.g. benzyl phenyl ketone) e.g. by chromatography. n COPYRIGHT: (C)1987,JPO&Japio |
| priorityDate | 1985-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.