http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6192578-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1984-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f257e63f6f2ea4841148a14cac14be01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a48cb8be90afcd3b9f41ff9c47b2ea2 |
| publicationDate | 1986-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6192578-A |
| titleOfInvention | Production of optically active 4-hydroxycyclopentenones |
| abstract | PURPOSE: To obtain the titled compound useful as an intermediate for agricultural chemicals, perfume, and drugs such as prostaglandin derivatives, etc., by hydrolyzing asymmetrically a specific cyclopentenone ester by the use of an enzyme or a microorganism. n CONSTITUTION: 1 equivalent dl-4-hydroxycyclopentenone shown by the formula I (R is 1W7C straight-chain alkyl, alkenyl, or alkynyl) is reacted with 1W4 equivalents aliphatic carboxylic acid in the presence(absence) of a solvent by the use of a catalyst at -20W150°C, to give (A) a dl-cyclopentenone ester shown by the formula III (R' is alkyl or alkenyl which may be replaced with halogen). The component A is hydrolyzed with (B) an enzyme such as esterase produced from a microorganism belonging to the genus Pseudomonas, Aspergillus, etc. or a microorganism (e.g., lipase of Aspergillus) in a buffer solution such as 0.05W2M buffer aqueous solution of phosphate, etc., at 10W60°C for 10W70hr with vigorous stirring, to give the titled compound shown by the formula III (* is asymmetric carbon). n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5009530-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4957867-A |
| priorityDate | 1984-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.