http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6183180-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18a7d1606da2ec2ad08ae63822efb00e |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
filingDate | 1984-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_267762840072a2a7b77d81f24581f3ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_204c901ee5bea51cabf2713d8921ba42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f77edf09ccea887081a23f47ca35c627 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf192291299b9b27aeb07be499014495 |
publicationDate | 1986-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6183180-A |
titleOfInvention | Isochroman derivative and its preparation |
abstract | NEW MATERIAL:A compound of formula I (R 1 is H, lower alkyl, aryl; R 2 , R 3 are H, alkyl, aryl, aralkyl). n EXAMPLE: 1-[2-(N-benzylamino)propyl]isochroman. n USE: Since it has powerful inhibition of gastric juice excretion, the compound is very effective in treatment or prevention for hyperacid, gastric ulcer and duodenal ulcer. n PREPARATION: The reaction of 1-ethoxyisochroman with a carbonyl compound is effected, the product of formula II is allowed to react with an amine of R 3 NH 2 , then the resultant Schiff base of formula III is reduced to give of formula I when R 2 is H. Or the compound of formula II is reduced, then halogenated and the product of formula IV (X is halogen) is allowed to react with an amine of formula V to give the compound of formula I. n COPYRIGHT: (C)1986,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5860611-A |
priorityDate | 1984-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.