http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6178733-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d6256baf554e46784d8daa478a2ddc6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate | 1984-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94bcac30f9fb148cd00aa8b5c313f9ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bca7215056fe3f97cb834316fe35a80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_767bfdfb19def810ca8080ac21a1bdfd |
| publicationDate | 1986-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6178733-A |
| titleOfInvention | Amorphous solid soluble in intestine |
| abstract | PURPOSE: To obtain the titled solid free from the gastric damage caused by the oral administration of a non-steroidal anti-inflammatory agent, by compounding a pH-dependent polymeric compound to a non-steroidal anti- inflammatory agent. n CONSTITUTION: The objective amorphous solid soluble in the intenstine, contains a non-steroidal anti-inflammatory agent (e.g. indomethacin) and one or more pH-dependent polymeric compounds (e.g. hydroxypropylene methylcellulose) at a weight ratio of 1:0.1W5. The oral administration of a non-steroidal anti- inflammatory agent occasionally causes gastric damage such as gastric ulcer, however, the above solid preparation causes little gastric damage even by oral administration. The solid can be prepared easily by dissolving a non-steroidal anti-inflammatory agent and one or more pH-dependent polymeric compounds in an organic solvent (eg. dichloromethane), and removing the organic solvent from the solution. n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0656138-U http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007331510-A |
| priorityDate | 1984-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.