http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6172773-A

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filingDate 1984-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4e56a7b300b503c2e8d743b245d5d0c
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publicationDate 1986-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S6172773-A
titleOfInvention Piperazine derivative and vasodilator containing it
abstract NEW MATERIAL:A piperazine derivative shown by the formula (Y is pyrrolidyl, or lower alkylamino). n EXAMPLE: 1-[ 5-(3,4,5-Trimethox6yphenyl)-2,4-pentadienoyl ]-4-(py-rr-olidinocarbonyl methyl)-piperazine. n USE: A vasodilator useful for remedying and preventing blood vessel disorder such as cerabrovascular disorder, coronary vessel disorder, peripheal circulatory disorder, etc. found in sequelae of cerebral infarct, myocardial infarction, arterial appeandicular clausura, etc. n PREPARATION: Thiazolidinethioamide of 5-(3,4,5-trimethoxyphenyl)-2,4- pentadienoic acid is reacted with piprazine to give 1-[5-(3,4,5- trimethoxyphenyl)-2,4-pentadienoyl]piperazine, which is condensed with a com pound shown by the formula ClCH 2 COY, to give a compound shown by the formula. n COPYRIGHT: (C)1986,JPO&Japio
priorityDate 1984-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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