http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6167-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
| filingDate | 1984-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bcf517183e80dfa70d3b03d1518380b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae403f29c353ec678d2c4dee0b0f236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f607955937b4df2309a512d5fd5babd8 |
| publicationDate | 1986-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6167-A |
| titleOfInvention | Preparation of beta-lactam compound |
| abstract | PURPOSE: To obtain the titled compound which is a synthetic intermediate for carbapenem based antibiotics easily in high yield, by treating a 5-substituted- 3-oxo-2-azabicyclo[2.2.0]hexane, etc. with a reducing agent under basic solvolysis conditions. n CONSTITUTION: A 5-X 1 -3-oxo-2-azabicyclo[2.2.0]hexane or 5-X 2 -3-oxo-2-azabicyclo [2.2.0]hex-2-ene (X 1 is acyloxy or oxo; X 2 is acyloxy), e.g. a compound expressed by formula I (R 1 and R 2 are H or alkyl; R 3 is R 1 or alkenyl; A 1 is acyloxy and A 2 and A 3 are H or together linked or A 1 and A 2 are oxo and A 3 is H; A 4 is R 1 ) is reduced and saturated if the bond between the 5- and the 6-positions is double bond, and treated with a reducing agent in an alcohol solvent in the presence of an inorganic alkali or organic amine, etc. to give the aimed compound 4-(2-hydroxyethyl)azetidin-2-one, e.g., a compound expressed by formula II. n COPYRIGHT: (C)1986,JPO&Japio |
| priorityDate | 1984-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.