abstract |
2-Substituted thiazolidines compounds having formula Iwherein X is a CH<sub>2</sub>, O or S, R is hydroxy or an acyloxy, alkyloxy, alkenyloxy or alkinyloxy group, R, is hydrogen or a group of formulaR<sub>2</sub> is hydrogen or a free or esterified carboxy group, R<sub>a</sub> and R<sub>b</sub> are hydrogen or methyl, p is zero or 1, R<sub>3</sub> is hydrogen, a C<sub>1</sub>-C<sub>2</sub> alkylsulphonyl group, a phenyl or p-Cl phenyl, p-methylsulphonyl group or an acyl group; are useful as mucus regulating, antitussive and antibronchospastic agents. |