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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00
filingDate 1984-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c81f94e6764b1755a6882139f2b795d0
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publicationDate 1986-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S615093-A
titleOfInvention Novel corticoid derivative cyanated in the 21-position and its preparation
abstract NEW MATERIAL:A compound of formula I (A is formula II, III; Y is H, halogen; B is H, oxo, halogen in the α- or β-position, lower alkyl; R 1 is H, lower alkyl in the α- or β-position; R 2 is 1W8C alkyl, halogenated alkyl, alkoxy; the bond between C 1 and C 2 is single or double). n EXAMPLE: 21-Cyano-9α-fluoro-16β-methyl-1, 4-pregnadiene-11β, 17α-diol-3, 20-dione 17α-propionate. n USE: Remedy for dermatopathies: it has high safety. n PREPARATION: A sulfonate ester in the 21-position of formula IV (Z is 1W10C alkyl, halogenated alkyl) is allowed to react with a reagent releasing cyanide ion such as potasium cyanide, preferably in an aprotic solvent such as DMF at 0W120°C for 1W20hr. n COPYRIGHT: (C)1986,JPO&Japio
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priorityDate 1984-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 27.