| abstract |
NEW MATERIAL:The quinone derivative or hydroquinone compound of formula I (R<1> and R<2> are H, methyl or methoxy, or R<1> and R<2> together form -CH= CH-CH=CH-; R<3> is H or methyl; R<4> is (substituted) aliphatic group, aromatic group or heterocyclic group; R<5> is methyl, methoxy, hydroxymethyl or carboxy; Z is C=C, CH=CH, group of formula II, formula III, etc.; n is 0-10; m is 0-3; k is 0-5). EXAMPLE:6-(3,5,6-Trimethyl-1,4-benzoquinon-2-yl)-6-(2-thienyl)hexanoic acid ethyl ester. USE:Antiasthmic agent, antiallergic agent or cerebral cardio-vascular system improver. PREPARATION:The compound of formula I can be prepared by reacting the compound of formula II (R<6> is H, methyl, methoxymethyl, benzyl, etc.; R<7> is H, OH, methoxy, methoxymethyloxy, etc.) with an oxidizing agent. |