| abstract |
PURPOSE: To obtain the titled compound useful as an intermediate for medicines, etc., industrially and advantageously, in high yield, by reacting an aniline with an alcohol in the presence of a catalyst containing a specific metal oxide and copper or copper oxide supported on a carrier. n CONSTITUTION: An aniline expressed by formula I (X is H, halogen, lower alkyl or lower alkoxy; n is an integer 1W3) is reacted with an alcohol expressed by the formula ROH (R is alkyl or phenyl) in the presence of a catalyst containing at least one oxide of a metal selected from rare earth elements, cobalt, aluminum, beryllium, zirconium and molybdenum, an alkaline earth metal oxide and copper or copper oxide supported on a carrier to afford the aimed compound expressed by formula II. The above-mentioned catalyst has a long catalyst life and is capable of almost suppressing the formation of by- products. Therefore, the aimed compound can be industrially, economically and advantageously obtained. n COPYRIGHT: (C)1986,JPO&Japio |