| abstract |
NEW MATERIAL:An oxothiazolidine compound expressed by formula I [R<1> is acyl, dialkylaminoalkylcarbamoylalkyl, arylcarbamoylalkyl or morpholinyl carbonylalkyl or formula II [A is alkylene; n is 0 or 1; m is 2 or 3; X is =N-, =N( O)- or =CH-; R<2> is OH, alkyl, etc.], etc.; Y is -S-, -S( O)- or -SO2-]. EXAMPLE:1-(4-Oxo-3-thiazolidinyl)acetyl-4-diphenylmethylpiperazine. USE:A recognition activator. PREPARATION:For example, a novel compound expressed by formula III or a reactive derivative thereof at the carboxyl group or a salt thereof is reacted with a compound expressed by the formula R<a>H (R<a> is arylamino, heterocyclic amino, etc.) or a reactive derivative thereof at the amino group or a salt thereof to give a compound expressed by formula IV which is one of the compound expressed by formula I. |