http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61263977-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e45efeaa6a34dfd9d44fa29a7fe0c806 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 1985-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67485af2bd9ff1c8a61c88c817a23721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_912122ba492a64a83c3b5c0b1a01ed5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29656a3bc2ab2a7a1701cb37b7b476c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc421fcbd0c8cf1cc64df5225f1ada07 |
publicationDate | 1986-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S61263977-A |
titleOfInvention | Dihydroimidazo(1,2-a)pyrimidine derivative |
abstract | NEW MATERIAL:The compound of formula I [R is H, 1W5C alkyl, heteroaryl, phenyl, etc.; R 1 is cyano, alkoxycarbonyl, etc.; R 2 is 1W4C alkyl, hydroxymethyl, acetoxymethyl, etc.; R 3 is 1W4C alkyl, formyl, nitro, etc.; R 4 or group of formula II (Rc and Rd are 1W4C alkyl, etc.; m is 1W3); n is 0W3]. n EXAMPLE: Methyl 3-diethylaminomethylaminomethyl-7-methyl-5-(3-nitrophenyl)- 5,8-dihydroimidazo[1,2-a]pyrimidine-6-carboxylate hydrochloride. n USE: A medicine. A remedy for coronary or cerebral circulatory disease. It has calcium antagonistic action, hypotensive action, coronary and cerebral vasodilating action and cardiotonic action, etc., and has low toxicity. n PREPARATION: For example, the compound of formula I can be produced by carrying out the electrophilic substitution reaction of the compound of formula III with an electrophilic reagent, thereby introducing the substituent group of formula IV to the imidazole ring. n COPYRIGHT: (C)1986,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006124354-A3 |
priorityDate | 1985-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.