| abstract |
PURPOSE: An external preparation useful for remedying an abnormal disease of skin keratinization, containing urea, a phospholipid, water and a fat and oil component. n CONSTITUTION: 2W30wt%, preferably 5W20wt% urea is blended with 0.2W30wt%, preferably 1W20wt% phospholipid (e.g., extracted from soybean, corn or colza), 5W80wt% water (purified water) (preferably 30W80wt% in the case of O/W type or 5W15wt% in the case of W/O type), 5W60wt% fat and oil component (e.g., hydrocarbon such as liquid paraffin, solid paraffin, etc., aliphatic higher alcohol such as cetyl alcohol, etc., ester such as bees wax, etc.) in the case of O/W type or 70W92wt% fat and oil component in the case of W/O type, and, if necessary, a gelatinizing agent, etc., or antibiotic, etc., to give an external preparation. n EFFECT: Having much more increased remedying effect on an abnormal disease of skin keratinization than an external preparation using a synthetic surface active agent as a dispersant. n COPYRIGHT: (C)1986,JPO&Japio |