| abstract |
PURPOSE: To provide the titled inhibiting agent containing at least one kind of component selected from inosine and inosine monophosphate. n CONSTITUTION: A platelet coagulation inhibiting agent is obtained by using at least one kind of component selected from inosine and inosine monophosphate (IMP) as an active component, and adding 10W30pts.wt. of 5'-adenosine monophosphate to 100pts.wt. of the above component. The agent may be further incorporated with other nucleic acid (e.g. 5'-CMP, 5'-GMP, adenosine, 3'-AMP, etc.) or taurine, etc. A hot-water extract of shellfish meat, especially oyster meat contains the above nucleic acids at preferable ratios together with taurine, etc., and exhibits especially excellent platelet coagulation inhibiting effect. The agent is effective for the remedy and prevention of thrombosis of warm- blooded animal including human. It is administered at a dose of 1W500mg/kg daily in the case of oral administration. n COPYRIGHT: (C)1986,JPO&Japio |