| abstract |
PURPOSE: To obtain the titled compound having antienzyme activity, by protecting an easily synthesizable swainsonine or its relating compound with a hydroxyl-protecting group such as lower alkanoyl, lower alkanesulfonyl, etc., and eliminating the protecting group from the product. n CONSTITUTION: Swainsonine of formula V or its relating compound such as swainsonine of formula II wherein R 3 is H, castanospermine, 1- epicastanospermine of formula III wherein R 3 is H, 1-deoxynojirimycin, 1- deoxymannnonojirimycin, etc., can be produced by deprotecting the compound of formula I [the ring in formula is the group of formula II (R 3 is H or OH- protecting group), formula III or formula IV; R 1 and R 2 independently or together form OH-protecting group] under a condition not to cause the decomposition of the product. n COPYRIGHT: (C)1986,JPO&Japio |