http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61225182-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34243ed5d528597b57990d6901da658f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-00 |
| filingDate | 1985-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1497c14832f67d76f64efc2596dac6cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab9ac73e46467d8d2c03258c872f82b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dc39c8fce91015d965058b63ac8cccc |
| publicationDate | 1986-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61225182-A |
| titleOfInvention | Production of thiazole derivative |
| abstract | PURPOSE:To obtain the titled substance useful as a cardiac inexpensively in high yield, by reacting a thiazole derivative with a compound such as pyridine and a compound such as 2,2,2-trichloroethyl chloroformate, etc., and reacting the reaction product with sulfur, etc. CONSTITUTION:A thiazole derivative shown by the formula I (R1 is H, hydroxyl group, lower alkyl, aryl, acyl, amino, lower alkylamino, arylamino, etc.; R2 is H, or lower alkyl) is reacted with a compound shown by the formula A-X<1> [A is group shown by the formula II (X is halogen; n is 1-3); X<1> is halogen] and a compound shown by the formula R3-H (R3 is nitrogen-containing hetero ring residue) at normal pressure under a temperature condition of environment by using preferably equimolar amounts of the compound shown by the formula I and the compound shown by the formula A-X' and >= an equimolar amount of the compound shown by the formula R3-H to give a compound shown by the formula III (R3' is dihydro derivative residue of nitrogen-containing hetero ring). Then, this compound is reacted with sulfur, or reacted with zinc and oxidized, to give the aimed compound including a novel compound shown by the formula IV. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0174811-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102174028-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7495018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7381725-B2 |
| priorityDate | 1985-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.