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filingDate 1984-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00c7c97a7f3713c38ba6f27098b3941e
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publicationDate 1986-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S6122041-A
titleOfInvention 1,4-benzoquinone derivative
abstract NEW MATERIAL:The compound of formula I [R 1 , R 3 , R 4 and R 6 are lower alkyl; R 2 and R 5 are H, lower alkyl or OH-lower alkyl; A is 3W12C alkylene or group of formula II (B and D are 1W10C alkylene)]. n EXAMPLE: 2,2'-Pentamethylene bis(3,6-dimethoxy-p-benzoquinone). n USE: Drug having low toxicity and useful as arachidonic acid 5-lipoxygenase inhibitor, antiasthma, tissue metabolism promoting agent, hypotensor, remedy for cardiac insufficiency, cerebral circulation improver, analgesic, antiulcer agent, etc. n PREPARATION: The compound of formula I wherein R 2 and R 5 are H or lower alkyl and A is group of catalyst II can be prepared by (1) reacting the compound of formula V (R 2 ' is H or lower alkyl; E is methoxymethyl) with the compound of formula VII (R 5 '=R 2 ') to obtain the compound of formula VIII, (2) demethoxymethylating the product with an acid, and (3) oxidizing the resultant compound of formula IX with an oxidizing agent. n COPYRIGHT: (C)1986,JPO&Japio
priorityDate 1984-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 40.