http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61210094-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de38b00c989d08f42dfc28157c832262 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate | 1986-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6ec7fa0a78762e98ae88db3710e5ad5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90af6dbdd1791f2b4df086a07ab55a6f |
| publicationDate | 1986-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61210094-A |
| titleOfInvention | Novel macrolide derivative, production thereof, and antibacterial composition containing same |
| abstract | NEW MATERIAL:The compound of formula I [R is 2W7C alkanoyl, or benzoyl (substituted with 1W4C alkyl, halogen, 1W4C alkoxy or NO 2 ); R 1 is H or group of formula II; R 2 is group of formula III]. n EXAMPLE: 9-O-acetyl-9-dihydrotylosin. n USE: An antibacterial agent having strong antibacterial activity especially against Gram-positive bacteria. n PREPARATION: The objective compound of formula I can be produced by acetalizing (or thioacetalizing) the 20-aldehyde group of tylosin (or demycarosyltylosin), acylating the 2'-OH on the 5-mycarosyl substituent group, silylating the product of obtain 2'-O-acyl-3,3",4",4'''-tetra-O-silyl-tylosin, reducing the 9-ketone group thereof to a secondary alcohol, acylating with an acylation agent (e.g. acetic anhydride) corresponding to the group R, and selectively removing the 2-acyl group and the 20-acetal group from the product. n COPYRIGHT: (C)1986,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002543212-A |
| priorityDate | 1985-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.