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filingDate 1985-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9efca45a36c85a453f0d2ae1b84cfea2
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publicationDate 1986-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S61204172-A
titleOfInvention 5-fluorouracil derivative
abstract NEW MATERIAL:The 5-fluorouracil derivative of formula I (R 1 and R 2 are H or lower alkyl; n is 0 or 1). n EXAMPLE: 1-(4, 4-Dimethyl-6-oxo-1-cyclohexenyl) methylcarbamoyl-5-fluorouracil. n USE: An orally administrable substance having antitumor activity. It is a drug administrable at an arbitrary controllable dose and having low toxicity and high safety. n PREPARATION: The compound of formula I can be produced by reacting the 5-fluorouracil of formula II with the compound of formula III in a polar solvent such as dimethylformamide (preferably dehydrated sufficiently with a dehydration agent) at a temperature between room temperature and 100°C. n COPYRIGHT: (C)1986,JPO&Japio
priorityDate 1985-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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