http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61197592-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 |
filingDate | 1985-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b286a0a0f7c941fd0e588822fe5b97ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a5413caefad16a0063267bf7cc51779 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_325ed28a54bee72b0ec2f41089b93d9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15c39380a6748922a89acf3673667f56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07acd45dd1c4cc155e030a761f04a8b7 |
publicationDate | 1986-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S61197592-A |
titleOfInvention | Production of alpha-l-aspartyl-l-phenylalanine methyl ester |
abstract | PURPOSE: To obtain the titled substance (α-APM) useful as a sweetener, with simple process, in high yield and quality, by a specific method using an α,β-mixture of N-formyl-L-aspartyl-L-phenylalanine as a raw material. n CONSTITUTION: An N-formyl-α-L-aspartyl-L-phenylalanine containing 5W30% β-isomer is treated with an acid (e.g. hydrogen chloride) in methanol preferably at 20W60°C for 1W30hr to effect the deformylation and diesterification. The produced L-aspartyl-L-phenylalanine dimethyl ester is hydrolyzed with hydrochloric acid preferably at 10W40°C usually for 1W10 days. The amount of the hydrochloric acid is preferably 1W5mol based on 1mol of the α,β-mixture used as the raw material. The objective α-APM can be produced by neutralizing the precipitated α-APM hydrochloride with sodium carbonate, etc. n COPYRIGHT: (C)1986,JPO&Japio |
priorityDate | 1985-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.