http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61191667-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_313f69d47526fdea2a26937b1eabf40b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-40 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25 |
filingDate | 1985-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb45adef8b7b1398618c171ecb7864d3 |
publicationDate | 1986-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S61191667-A |
titleOfInvention | Urea compound |
abstract | NEW MATERIAL:A compound shown by the formula I (X 1 and X 2 are halogen; R is hydrocarbon group). n EXAMPLE: N-[p-Bis(β-chloroethyl)aminophenyl]-N'-(β-chloroethyl) urea. n USE: A carcinostatic agent, having safe and improved carcinostatic action free from toxicity, capable of being administered orally or parenterally, or locally. A dose is 800W0.002mg/kg/day. n PREPARATION: A substituted aniline shown by the formula II is reacted with a β-haloethylisocyanate shown by the formula III in a solvent such as hexane, etc., at -20W100°C to give a compound shown by the formula I. The compound shown by the formula I is usually solid showing white, light yellow, light yellowish brown, or light brown, having a fixed melting point, soluble in acetone, N,N-dimethylformamide, methanol, etc., slightly soluble in ligroin, hexane, chloroform, etc., and almost insoluble in water. n COPYRIGHT: (C)1986,JPO&Japio |
priorityDate | 1985-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.