| abstract |
NEW MATERIAL:The compound of formula I (R is 3- or 4-pyridyl; R 1 is H, alkyl, lower alkoxycarbonylalkyl or cyanoalkyl; R 2 is alkyl, chloroethyl, alkenyl, phenetyl, furfuryl, benzyl, phenyl, etc.). n EXAMPLE: N-(1-methoxyethylamino-2,2,2,-trichloroethyl)nicotinamide. n USE: Bacteriosis-controlling agent for agricultural and horticultural use. n PREPARATION: The compound of formula I can be prepared by (1) reacting nicotinamide or isonicotinamide of formula II with chloral in an inert solvent at 30W150°C to obtain the compound of formula III, (2) reacting the compound with a halogenation agent in an inert solvent at 50W80°C, and (3) reacting the resultant compound of formula IV with the compound of formula R 1 R 2 NH in an inert solvent at 0W150°C for 30minW10hr, preferably in the presence of a dehydrohalogenation agent. n COPYRIGHT: (C)1986,JPO&Japio |