| abstract |
PURPOSE: In a method where a nitrile compound is reacted with water and converted into an amide compound by the action of a bacterium having nitrilase activity, to produce industrially the amide, by irradiating a mold to be used with light rays with given wavelength. n CONSTITUTION: A nitrile compound is reacted with water and converted into a corresponding amide compound by the use of a bacterium belonging to the genus Corynebacterium, Nocardia, Bacillus, Bacteridium, etc., having nitrilase activity, and positive Gram stain properties. In the operation, a mold to be used is irradiated with light rays with about 300W450nm wavelength before completion of hydration reaction, and exposed to light energy having about 2×10 -3 W about 1×10 -2 ×E/g mold.sec. The reaction is carried out in a container consisting at least partially of a material of no light transmission, and acetonitrile, propionitrile, benzonitrile, malononitrile, etc. are used as the nitrile compound. n COPYRIGHT: (C)1986,JPO&Japio |