http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61155353-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb4ee28d43b5e8d4a3c5141fa9bcfeb0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C53-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-27 |
| filingDate | 1984-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c950ce012ff8e9eb1fe0aded8e2c1a52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aab46e61d0b1d818ce81992146c5797a |
| publicationDate | 1986-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61155353-A |
| titleOfInvention | Beta, beta-difluoro-gamma,delta-unsaturated carboxylic acid ester |
| abstract | NEW MATERIAL:A compound shown by the formula I (R 1 WR 4 are H, alkyl, or R 1 and R 3 may be linked to form ring; R 5 is lower alkyl). n EXAMPLE: 3,3-Difluoro-4-hexadecenoic acid methyl ester. n USE: An intermediate for synthesizing especially a β,β-difluoro saturated carboxylic acid, a β-oxidation inhibitor to inhibit β-oxidatation in substance metabolism in a biochemical field. n PREPARATION: For example, an α-acetoxyaldehyde or ketone shown by the formula II is difluoromethylated with (Me 2 N) 3 P and CF 2 Br 2 in a solvent such as tetrahydrofuran, etc., to give a compound shown by the formula III, which is then saponified to give a 1,1-difluoro-1-alkene-3-ol shown by the formula IV. This compound is subjected to Claisen rearrangement in a solvent such as toluene, etc., in the presence of R 4 CH 2 C(OR 5 ) 3 and a propionic acid CH 3 CH 2 COOH acid to give a compound shown by the formula I. n COPYRIGHT: (C)1986,JPO&Japio |
| priorityDate | 1984-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.