http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61152698-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
filingDate | 1984-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15c39380a6748922a89acf3673667f56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a5413caefad16a0063267bf7cc51779 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_325ed28a54bee72b0ec2f41089b93d9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07acd45dd1c4cc155e030a761f04a8b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b286a0a0f7c941fd0e588822fe5b97ac |
publicationDate | 1986-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S61152698-A |
titleOfInvention | Production of alpha-l-aspartyl-l-phenylalanine methyl ester |
abstract | PURPOSE: N-Formyl-α-L-aspartyl-L-phenylalanine is treated with methanol-HCl and the main product is hydrolyzed to give the titled compound in high yield through an industrially simplified process. n CONSTITUTION: N-Formyl-α-L-aspartyl-L-phenylalanine is treated with methanol-HCl, preferably at 20W60°C for 1W30hr to effect deformylation and diesterification to form α-L-aspartyl-L-phenylalanine dimethyl ester as a major product. Then, the resultant dimethyl ester is hydrolyzed in hydrochloric acid to give the objective compound. n EFFECT: There is no problem on stability, because L-phenylalanine methyl ester is not used. n COPYRIGHT: (C)1986,JPO&Japio |
priorityDate | 1984-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.