http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61152660-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34243ed5d528597b57990d6901da658f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
| filingDate | 1984-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1497c14832f67d76f64efc2596dac6cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d900774d643cd0434b98127f3e1f1134 |
| publicationDate | 1986-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61152660-A |
| titleOfInvention | Bis-dioxopiperazine derivative |
| abstract | NEW MATERIAL:The compound of formula I [R1 and R2 are H or lower alkyl, provided that both R1 and R2 are not lower alkyl at the same time; R3 is H or group of formula II; (a) when both R1 and R2 are H and R3 is group of formula II, then R4 is (CH2)nR5 or group of formula III-IV, etc.; R5 is lower alkoxy, phenylthio, etc.; R6 and R7 are H or lower alkyl, or R6 is phenyl, etc.; R8 is H, lower alkylcarbonyl, etc.; R9 is lower alkoxy, NH2, etc.; (b) when both R1 and R2 are lower alkyl and R3 is group of formula II, then R4 is lower alkyl, phenyl, lower alkoxy, etc.; and (c) when R3 is H, then R4 is the groups of R4 in the case (b) except for lower alkyl] and its non-toxic salt. EXAMPLE:1,2-bis[4-[ 2-(N-Methoxycarbonyl)aminoacetoxymethyl ]- 3,5-dioxopipe razin-1-yl]ethane. USE:An antitumor agent suitable for drug preparation. PREPARATION:The compound of formula I can be prepared by condensing the compound of formula V with the compound of formula R4COOH in the presence of a condensation agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8704707-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-642519-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5393889-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9200971-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5438057-A |
| priorityDate | 1984-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.