| abstract |
NEW MATERIAL:The compound of formula I (Z is residue of aminodicarboxylic acid excluding the amino group; X is residue of tetrapyrrole excluding the carboxyl group; n is 1W4). n EXAMPLE: Monoaspartylchlorin e 6 . n USE: Antitumor agent and optical diagnostic. n PREPARATION: The objective compound can be prepared by contacting a tetrapyrrole containing ≥3 carboxyl groups [e.g. the compound of formula II (X is H, vinyl, ethyl, acetyl or formyl; Y is methyl or formyl; M is methyl; E is ethyl)] with an aminodicarboxylic acid in the presence of a proper solvent. n COPYRIGHT: (C)1986,JPO&Japio |