| abstract |
PURPOSE: An antitumor agent comprising a specific compound including well- known benzydamine hydrochloride well-known as an anti-inflammatory agent, as an active ingredient. n CONSTITUTION: A compound shown by the formula I (R 1 and R 2 are H, 1W4C alkyl, halogen, or methoxy; n is 1W4) is used as an antitumor agent. Especially benzydamine derivative shown by the formula II is a representative compound. the compound shown by the formula I is found to have effects or reduction in number of tumor cells, prolongation of life, and inhibition of tumor multiplica tion, etc. in tumor of animal and human, and to be useful as an antitumor agent. A dosage form for administration may be either oral or parenteral admin istration. A dose is preferably 0.1W300mg/kg/day. n COPYRIGHT: (C)1986,JPO&Japio |