http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61112015-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13acffa0e4ce30d3be128ccd86b384f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df039a3bba404699e360a74b0bea24a6 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 |
filingDate | 1985-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ed78c3209e3363aaf4ce5d84b47841f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb2a9ca43a6dc4eb052374a2795ae749 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e60e722fcdcdea8f70158686ad2584d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57db98509f048cece545728d3c8aa886 |
publicationDate | 1986-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S61112015-A |
titleOfInvention | Pharmaceutical preparation |
abstract | PURPOSE: To provide a pharmaceutical preparation for transcutaneous absorption and capable of releasing isosorbid dinitrate (a medicine of stenocardia) slowly at a constant rate for a long period, by applying an adhesive base layer containing the drug to the surface of a polyester film and coating the base layer with a polymer layer through which the drug can be migrated. n CONSTITUTION: A surface of a polyester film having a thickness of preferably 6W9μm is coated with a base layer containing 1W25wt% isosorbide dinitrate (ISDN) effective for the suppression and prevention of the fit of stenocardia. In the above preparation, the adhesive surface of the base layer is coated with a polymer such as an ethylene-vinyl acetate copolymer having a vinyl acetate content of preferably 22W40wt% to control the ISDN content in the base layer and prevent the crystallization of ISDN. A pharmaceutical preparation having excellent adhesivity to the skin and moderate drug solubility and drug releasability, and free from the problems such as stimulation or staining of the skin, can be prepared by this process. n COPYRIGHT: (C)1986,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02142434-U http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6471907-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0334923-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0304227-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0754259-Y2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02227230-A |
priorityDate | 1985-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.