http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61109763-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C325-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate | 1984-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d891ad7bcbadc770040baefecc2b6bd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e52ecde6a64d6f639013832142f314b |
| publicationDate | 1986-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S61109763-A |
| titleOfInvention | Beta-aminothiol ester and its preparation |
| abstract | NEW MATERIAL:The compound of formula I (R 1 is alkyl or aryl; R 2 and R 3 are protecting group). n EXAMPLE: 3-Benzylamino-5-benzyloxy-2-(1-hydroxyethyl)pentanoic acid phenylthio ester. n USE: A synthetic intermediate of carbapenem-type β-lactam antibiotic substance exhibiting excellent antibacterial activity against almost all bacterial strains including Pseudomonas aeruginosa and having excellent β-lactamase-stabilizing effect. n PREPARATION: The compound of formula I can be prepared by (1) reacting the β-hydroxythiol ester of formula II with the boron compound of formula III (R and R' are alkyl, cycloalkyl or together with bonded boron atom from a ring) at -78°C W room temperature in the presence of a tertiary amine, (2) reacting the reaction product with the imine of formula IV, and (3) treating with hydrogen peroxide at -25°C W room temperature. n COPYRIGHT: (C)1986,JPO&Japio |
| priorityDate | 1984-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID54451806 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID235921716 |
Total number of triples: 17.